| RESEARCH METHODOLOGY |
|
| Year : 2014 | Volume
: 5
| Issue : 2 | Page : 88-90 |
|
|
Up-dosing of non-sedating antihistamines in chronic urticaria: Need for well-designed clinical trials in India
Anant D Patil
Freelance Consultant: Medical Communication and Training, Navi Mumbai, India
Correspondence Address:
Anant D Patil
B-101, Balaji Bhavan CHS, Sector 44 A, Nerul, Mumbai, Maharashtra
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2229-3485.128029
|
|
|
Urticaria is a heterogeneous group of diseases. Chronic urticaria significantly impacts quality-of-life of patients. Second generation, non-sedating antihistamines are recommended as first line treatment for chronic spontaneous urticaria. In patients with inadequate control of symptoms, increase in dosage of non-sedating antihistamines up to four fold has been recommended. This recommendation is based on low cost, good safety and good evidence of efficacy of non-sedating, second generation antihistamines. This article reviewed Indian data on up-dosing of antihistamines in chronic urticaria. There is a need for well-designed clinical trials with up-dosing of individual antihistamines in Indian patients. |
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
