Perspectives in Clinical Research

RESEARCH METHODOLOGY
Year
: 2014  |  Volume : 5  |  Issue : 2  |  Page : 88--90

Up-dosing of non-sedating antihistamines in chronic urticaria: Need for well-designed clinical trials in India


Anant D Patil 
 Freelance Consultant: Medical Communication and Training, Navi Mumbai, India

Correspondence Address:
Anant D Patil
B-101, Balaji Bhavan CHS, Sector 44 A, Nerul, Mumbai, Maharashtra
India

Urticaria is a heterogeneous group of diseases. Chronic urticaria significantly impacts quality-of-life of patients. Second generation, non-sedating antihistamines are recommended as first line treatment for chronic spontaneous urticaria. In patients with inadequate control of symptoms, increase in dosage of non-sedating antihistamines up to four fold has been recommended. This recommendation is based on low cost, good safety and good evidence of efficacy of non-sedating, second generation antihistamines. This article reviewed Indian data on up-dosing of antihistamines in chronic urticaria. There is a need for well-designed clinical trials with ­up-dosing of individual antihistamines in Indian patients.


How to cite this article:
Patil AD. Up-dosing of non-sedating antihistamines in chronic urticaria: Need for well-designed clinical trials in India.Perspect Clin Res 2014;5:88-90


How to cite this URL:
Patil AD. Up-dosing of non-sedating antihistamines in chronic urticaria: Need for well-designed clinical trials in India. Perspect Clin Res [serial online] 2014 [cited 2022 Aug 19 ];5:88-90
Available from: http://www.picronline.org/article.asp?issn=2229-3485;year=2014;volume=5;issue=2;spage=88;epage=90;aulast=Patil;type=0